Are you trying to improve sound quality, or add functionality?
If sound quality, as ctuna said, the HU is not the weakest link. You can keep your OEM HU and upgrade amp/speakers. Tons of threads here.
BUT, if you want functionality you currently don't have (Bluetooth phone and audio streaming, USB, etc), then HU may be the easiest ( or possibly only) way forward.
Ultimately, to answer your Q, I'm not aware of any specific single din units that blend and integrate well.
Personally, I installed a pioneer avic, and hear lots of great things about the dynavin units. Both double din, but dynavin looks pretty OEM.
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